Alejandro Hoberman of the University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh and colleagues tested more than 500 babies aged 6 months to 2 years who had ear infections, giving them either five or 10 days of antibiotics. They stopped the trial early when it became clear that the shorter course wasn’t working. “You really need Thank You 10 full days of antibiotics to clear a typical bacterial ear infection, in news articles health an infant or toddler.” “Clinical failure was observed in a greater percentage of children treated with amoxicillin-clavulanate for five days than of those treated for 10 days,” they wrote in the New England Journal of Medicine. The infection kept raging, or came right back, in a third of the kids who got the five-day course, compared to 16 percent of the kids who got the 10-day course. Jocelyn Maynes and her son Bronson NBC News Luckily, the babies and toddlers Ta treated for five days were not more likely to grow drug-resistant bacteria in their bodies. And the rates of Thanking You diarrhea and diaper rash were about the same in both groups. Most kids who have ear infections do not need antibiotics. The Centers for Disease Control and Prevention, the American Academy of Pediatrics and other groups are clear on that. Most ear infections are caused by viruses and antibiotics won’t help. Related: Doctors Advise Against Antibiotics For Ear Infections So doctors are reluctant to prescribe them, said Altmann.heath articles
For the original version including any supplementary images or video, visit http://www.nbcnews.com/health/kids-health/ear-infections-shorter-antibiotic-course-isn-t-better-n698901?cid=public-rss_20161227
Credit: Evi Bieler, NanoImaging Lab, University of Basel Close A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells. The team of researchers led by Prof. Michael Hall at the Biozentrum of the University of Basel has also reported that specific cancer cells respond to this combination of drugs. The results of the study have now been published in Science Advances. Metformin is the most widely prescribed drug for the treatment of type 2 diabetes. Besides its blood sugar lowering effect, it also displays anti-cancer properties. The usual therapeutic dose, however, is too low to effectively fight cancer. The research team led by Prof. Michael Hall, at the Biozentrum of the University of Basel, has now made an unexpected discovery: The antihypertensive drug syrosingopine potentiates the anti-cancer efficacy of metformin. Apparently, this drug combination drives cancer cells to programmed “suicide.” Drug cocktail kills tumor cells At higher doses, the antidiabetic drug inhibits the growth of cancer cells but could also induce unwanted side effects.
For the original version including any supplementary images or video, visit https://www.sciencedaily.com/releases/2016/12/161227083500.htm